OCT定量检测对糖尿病白内障患者视网膜神经纤维厚度的价值

摘要

目的：：应用光学相干断层扫描仪( optical coherence tomography,OCT)定量检测老年白内障患者视网膜神经纤维层( retinal nerve fiber layer,RNFL)厚度的变化,分析年龄相关性白内障患者实施超声乳化吸除手术后盘周RNFL的变化特点以及与视力的相关性。方法：临床纳入实施超声乳化吸除手术的老年年龄相关性白内障患者51例70眼,根据患者有无糖尿病分为糖尿病组与非糖尿病组。其中,非糖尿病组30例38眼,糖尿病组21例32眼。所有患者术后均采用OCT定量测量不同时间(术后3、14d,1、3、6mo)眼底盘周RNFL的厚度,比较不同时间RNFL厚度的变化,分析其与术眼最佳矫正视力( BCVA)的相关性。结果：非糖尿病组术后3、14 d盘周RNFL厚度与糖尿病组对比无统计学差异( P>0.05),术后3、6 mo盘周RNFL厚度明显小于糖尿病组(P0.05)；糖尿病组术后3、6 mo裸眼视力明显低于非糖尿病组,差异有统计学意义(P0. 05);at 3 and 6mo after treatments, RNFL thickness of non-DM group was smaller than that of DM group (P0. 05);the uncorrected visual acuity of DM group at 3, 6mo postoperatively was significantly lower than those of non-DM group(P<0. 05); at 14d, 1 and 3mo after treatments, the RNFL thickness of non-DM group was negatively correlated with the patient′s visual acuity (P<0. 05); at 14d, 1, 3 and 6mo after treatments, RNFL thickness of DM group was negatively correlated with the patient′s visual acuity (P<0. 05).CONCLUSlON: OCT is a good detecting parameter for the change of RNFL thickness and the change of RNFL thickness is an important cause of the changes of the patient′s visual acuity.