使用Oculus Keratograph 5M测量圆锥角膜患者NITBUT和TMH

摘要

目的:比较圆锥角膜患者和正常人使用Oculus Keratograph 5M(K5M)测得的非侵入性泪膜破裂时间(NITBUT)和泪河高度(TMH),以确定这两项指标和圆锥角膜的关系.方法:50例100眼圆锥角膜患者和50例100眼正常人参加了这项研究.圆锥角膜组患者的年龄为15~60(平均28.33±8.60)y.对照组为18~60(平均26.25±1.11)岁.使用K5M测量所有受试者的NITBUT和TMH.结果:两组之间的NITBUT和TMH平均值差异无统计学意义(P=0.58,0.69).两参数的相关性研究显示,两组中NITBUT和TMH之间均无相关性(圆锥角膜组: r=0.053, P=0.721;对照组: r=-0.0501, P=0.7098).结论:研究显示圆锥角膜对泪液质量和数量都没有显著的临床影响.%AIM:To compare the non-invasive tear break-up time (NITBUT) and tear meniscus height (TMH) measurements in keratoconus patients and normal subjects, and to determine the relationship between these measurements with keratoconus disease by the Oculus Keratograph 5M (K5M).METHODS:Fifty keratoconus patients (100 eyes) and 50 healthy subjects (100 eyes) participated in the study.The age range in keratoconus group was 15-60(mean ± standard deviation=28.33±8.60) y, and in control group was 18-60(26.25±1.11) y.The measurements of NITBUT and TMH were performed using the K5M.RESULTS:The mean value of NITBUT between the keratoconus group and the control group showed no statistically significant different (P=0.58).Also, the mean of TMH between two groups was not significantly different (P=0.69).The results of correlation coefficient between the variables of the study demonstrated that there was no significant relationship between the NITBUT and TMH measurements with the two groups (keratoconus group:r=0.053, P=0.721;control group;r=-0.0501, P=0.7098).CONCLUSION:Our study shows that the presence of keratoconus has no clinically significant impact on the quality and quantity of tear film.