脉络膜转移癌的荧光素和吲哚菁绿血管造影的影像分析

摘要

· AIM: To compare the imaging features of fundus fluorescein angiography ( FFA ) and indocyanine green angiography ( ICGA ) in choroidal metastases, and to provide the basis for the accurate diagnosis of choroidal metastases. ·METHODS: Six patients (8 eyes) with definite primary malignant tumor lesion were diagnosed, and fundus photographs were taken after mydriasis. FFA and ICGA were simultaneously contrasted with Heidelberg fundus angiography to compare the similarities and differences between the two imaging examinations. ·RESULTS: FFA showed a low fluorescence at the early stage, a needle-like or spot-like fluorescence at the middle stage and a strong fluorescence band at the late stage, and a weak fluorescence at the edge of the lesion in some cases. The ICGA showed a low fluorescence. There was no significant change in intensity, only 1 case in the reverse phase of the central and focal lesions around the strong fluorescence. ·CONCLUSION: FFA and ICGA for choroidal metastases have a more characteristic performance, both helpful for the diagnosis of choroidal metastases.%目的：比较脉络膜转移癌的荧光素眼底血管造影( FFA)及吲哚菁绿血管造影( ICGA )的影像特点，为该疾病的准确诊断提供依据。　　方法：经临床诊断，有明确原发恶性肿瘤病灶的患者6例8眼，散瞳后行眼底照相，用海德堡眼底血管造影仪行FFA及ICGA同步造影，比较两种影像学检查的异同。　　结果：FFA早期显示瘤体为低荧光，中期呈现针尖样或斑点样荧光，晚期表现为斑驳样强荧光，部分病例病灶边缘呈强荧光环带；ICGA显示的病灶表现为低荧光，整个造影过程中荧光强弱无明显变化，仅有1例病例在反转期出现中央及病灶周围的点状强荧光。　　结论：FFA和ICGA对于脉络膜转移癌有较为特征性的表现，二者结合有助于脉络膜转移癌的诊断。