糖尿病性黄斑水肿激光治疗前后视网膜功能的定量研究

摘要

目的：探讨激光光凝对糖尿病黄斑水肿患者视网膜功能的影响。　　方法：连续选取2010-03/2014-03我院眼科经眼底血管造影检查确诊为糖尿病性黄斑水肿行黄斑格栅光凝的患者19例30眼,于治疗前及黄斑格栅光凝治疗后3 mo均行多焦视网膜电图检查,并对其结果进行统计学分析。　　结果：激光治疗后中心凹处 a、b 波振幅密度升高,与治疗前相比存在统计学差异( t=-3.7683, P0.05；t=1.5623,P>0.05)。激光治疗后黄斑区a、b波振幅密度均升高,与治疗前相比存在统计学差异(t=4.8337,P0.05；t=-0.1766,P>0.05)；激光治疗后黄斑外区a、b波潜伏期均延长,与治疗前相比均存在统计学差异(t=-2.0905,P0. 05;t=1. 5623, P>0. 05 ). Compared with pretreatment, the amplitude densities of a-ware and b-ware at macular were statistically larger ( t=4. 8337, P0. 05;t=-0. 1766, P>0. 05). It was significant longer in the latency of a-wave and b-wave at paramacular after photocoagulation (t=-2. 0905, P<0. 05;t=-2. 5646, P<0. 05). · CONCLUSION: The laser photocoagulation treatment for DME can improve the retinal function at fovea, which benefits the vision acuity. Unfortunately, it induces extensively damaging effects on the macula and paramacular.