盐酸米诺环素软膏辅助治疗种植体周围炎12例

摘要

目的 评估盐酸米诺环素软膏治疗种植体周围炎的效果.方法 12例种植体周围炎患者(12枚种植体),彻底洁治,0.2%氯己定(洗必泰)冲洗,盐酸米诺环素软膏置入种植体周围袋袋底,分别在基线和治疗后4周测菌斑指数、龈沟出血指数和探诊深度,进行统计学分析.结果 菌斑指数、龈沟出血指数和探诊深度分别由治疗前(2.42±0.79)分,(3.08±0.67)分,(5.44±0.64) mm,治疗4周后显著下降至(0.91±0.67)分,(1.33±0.88)分,(3.98±0.78) mm,差异均有统计学意义(P＜0.05).结论 盐酸米诺环素软膏对种植体周围炎有较好辅助治疗作用.%Objective To assess the clinical outcomes of peri-implantitis treated with local administration of minocycline hydrochloride. Methods Twelve patients with one implant each and being diagnosed as peri-implantitis were locally treated with minocycline hydrochloride after debridement and rinsing with 0. 2% chlorhexidine solution. Plaque index, sulcus bleeding index, and probing depth were recorded at baseline and 4 weeks after the treatment, respectively. Results Plaque index, sulcus bleeding index, and probing depth were (2. 42±0. 79) , (3. 08±0. 67) , and (5. 44±0. 64) mm at baseline, and were (0. 91±0. 67) , (1.33±0. 88) , and (3.98±0. 78) mm at the forth week after the treatment, respectively. All differences were statistically significant ( P<0. 05 ) . Conclusion The local administration of minocycline hydrochloride can be applied to treat peri-implantitis effectively.