梅毒螺旋体阳性患者C反应蛋白的变化及意义

摘要

目的:观察梅毒抗体阳性患者C反应蛋白水平以探讨其对梅毒螺旋体感染的诊断意义及应用价值.方法:分别检测并比较75例梅毒抗体阳性患者、80例健康正常人c反应蛋白水平,并同时对比分析梅毒患者治疗前后c反应蛋白水平变化情况.结果:观察组梅毒患者治疗前CRP水平显著高于健康正常人组(P＜0.001).I期、Ⅱ期、Ⅲ期梅毒患者CRP水平有显著性差异(P＜0.01),随患者梅毒分期的增高,CRP水平有所降低.梅毒患者治疗前后CRP水平有统计学差异(P＜0.01).结论:CRP检测在梅毒抗体阳性患者早期诊断、临床分期及治疗转归等方面具有重要应用价值.%Objective: Observing the C-reaction protein( CRP) in patients with positive treponema pal-lidum to explore the value of CRP in the diagnosis of syphilis. Method: The level of CRP in 75 cases of positive treponema pallidum ,80 cases of health was detection, and also after the treatment of syphilis. Result: There was significant difference between the patients'of positive treponema pallidum and the health in the lev-el of CRP( P＜0. 001). There's evident difference in clinical stages of Ⅰ ,Ⅱ , Ⅲ ( P＜0. 001). Compared with the level of CRP in patients with positive treponema pallidum before treatment, there was obvious difference after treatment(P＜0.01). Conclusion: CRP testing to patients with positive treponema pallidum has application value in early diagnosis , the clinical stages ,and treatment outcome.