特布他林与布地奈德雾化吸入治疗慢性支气管炎临床疗效观察

摘要

目的:探讨特布他林与布地奈德雾化吸入治疗慢性支气管炎急性发作的临床疗效和安全性.方法:选取2010年6月至2012年6月在我院呼吸内科住院治疗的106例慢性支气管炎急性发作患者为研究对象,运用随机数字表法将符合本研究纳入标准和排除标准的患者分为对照组和实验组,对照组患者给予常规治疗,而实验组患者则特布他林与布地奈德雾化吸入治疗,治疗14d,观察并比较对照组和实验组患者临床治疗效果和不良反应发生情况.结果:治疗14d,实验组治疗总有效率(96.23%)明显高于对照组的(84.91%),对照组和实验组患者临床疗效差异有统计学意义(P<0.05),且对照组和实验组不良反应发生率差异无统计学意义(P>0.05).结论:特布他林与布地奈德雾化吸入治疗慢性支气管炎急性发作临床疗效确切,安全高效,药物不良反应少,值得进一步推广.%Objective: To investigate the curative effect of terbutaline and budesonide aerosol inhalation patients with chronic bronchitis. Method: The clinical data of one hundred and six patients with chronic bronchitis were collected who were treated in the department of breath internal medicine in our hospital from June 2010 to June 2012,then they were divided into the control group and the observation group by using a random number table, patients with chronic bronchitis in the control group were given conventional treatment, but patients with chronic bronchitis in the observation group were given terbutaline and budesonide aerosol inhalation on the basis of the control group, at last, its clinical efficacy and the incidence of adverse reactions were compared. Result: The total efficient rate was higher in the observation group than that in the control group ( 96. 23% vs 84. 91% ,P<0. 05 ),and there was no statistical significance in adverse reaction rate ( P> 0.05 ). Conclusion: Terbutaline and budesonide aerosol inhalation can obtain satisfactory curative effect on patients with chronic bronchitis, it is safe and reliable, it is worthy of applying for clinical.