C-反应蛋白血清前白蛋白血清降钙素原联合检测在感染性疾病中的应用

摘要

目的:探讨C-反应蛋白(CRP)、血清前白蛋白(PA)、血清降钙素原(PCI)联合检测在感染性疾病早期诊断中的临床价值.方法:选取2015至2016年收治的感染性疾病患者108例,分为病毒感染组43例与细菌感染组65例,选取同期健康体检者50例作为健康对照组.结果:细菌感染组患者的CRP、PCI明显高于其他两组(P<0.05)、PA明显低于其他两组(P<0.05),病毒感染组CRP、PCI水平明显高于对照组(P<0.05),病毒感染组与对照组PA无明显差异(P>0.05).分别以PCT>5ng/mL、CRP>50mg/L、PA<180mg/L为标准统计阳性率,细菌感染组患者阳性率均明显升高(P<0.05).结论:血清PCT、CRP与PA指标均可以用于感染性疾病的临床诊断,可以作为感染病原菌的区分,但联合检测方法的准确度更高.%Objective:To study the C -reactive protein (CRP), serum prealbumin (PA), serum cal-citonin original joint detection (PCI) in the diagnosis of infectious disease clinical value.Selection Methods:our hospital between 2015 and 2016 of 108 patients with infectious diseases were divided into viral infection group of 43 patients with bacterial infection group 65 examples, selecting the healthy physical examination were 50 cases for the same period as the healthy control group.Results:CRP, PCI in patients with bacterial infection group was obviously higher than that of other two groups ( P <0.05) , PA significantly lower than the other two groups (P < 0.05), the level of CRP, PCI virus infection group was obviously higher than that of control group ( P < 0.05) , the virus infection group and control group in the PA has no obvious difference ( P> 0.05).Respectively by PCT > 5 ng/ml, CRP > 50 mg/L, PA < 180 mg/L for the standard statistical posi-tive rate, positive rate of patients with bacterial infection group were significantly increased (P < 0.05).Con-clusion:the serum PCT and CRP and PA indexes can be used for clinical diagnosis of infectious disease, can be a distinction between infection of pathogenic bacteria, but joint detection methods with higher accuracy.