妊娠晚期孕妇颈围与脐动脉血流相关性分析

摘要

Objective To investigate the correlation between neck circumference of pregnant woman in late trimester of pregnancy and systolic/diastolic ratio (Vs/Vd) of umbilical artery.Methods One hundred and twenty-six pregnant women in late trimester of pregnancy were enrolled in the study.According to the neck circumference,these pregnant women were divided into two groups: group A (n=81) in which the pregnant women with neck circumference < 34.7cm,and group B (n=45) in which the pregnant women with neck circumference ≥34.7cm.The correlation between neck circumference of pregnant woman in late trimester of pregnancy and Vs/Vd ratio of umbilical artery was analyzed.Results The detection rate of Vs/Vd≥3.0 in group B was significantly higher than that in group A (64.4％ vs 19.8％,χ2=25.166,P<0.01).The multiple factor logistic regression analysis showed that neck circumference ≥34.7cm (r=5.167,95％,CI:2.138～12.491,P<0.01) was an independent risk factor of systolic/diastolic ratio≥3.0.After the pregnant women with pregnancy-related disease were excluded, the detection rate of Vs/Vd≥3.0 in group B was also significantly higher than that in group A (47.8％ vs 11.5％,χ2=14.728,P<0.01).The multiple factor logistic regression analysis showed that neck circumference ≥34.7cm (r=7.028, 95％CI:2.403～20.555,P<0.01) was an independent risk factor of systolic/diastolic ratio≥3.0.Conclusion The neck circumference of pregnant woman is closely correlated to Vs/Vd ratio of umbilical artery,which suggests that obesity is related with placental function abnormality, even in healthy pregnant women.%目的 探讨妊娠晚期孕妇颈围与脐动脉Vs/Vd比值的相关性.方法 126例妊娠晚期女性,按颈围分为颈围<34.7 cm组(n=81)和颈围≥34.7 cm组(n=45).分析妊娠晚期孕妇颈围与脐动脉Vs/Vd比值的关系.结果 颈围 ≥ 34.7cm组脐动脉Vs/Vd≥3.0检出率明显高于颈围<34.7 cm组(64.4％ vs 19.8％,χ2=25.166,P=0.000).多因素Logistic回归分析,颈围≥34.7 cm(Or=5.167,95％CI:2.138～12.491,P=0.000)是脐动脉Vs/Vd≥3.0的独立危险因素.排除合并妊娠相关疾病孕妇后,颈围 ≥ 34.7cm组Vs/Vd比值≥3.0检出率仍明显高于颈围<34.7 cm组(47.8％ vs 11.5％,χ2=14.728,P=0.000).多因素Logistic回归分析,颈围≥34.7 cm(Or=7.028, 95％CI:2.403～20.555,P=0.000)是Vs/Vd比值≥3.0的独立危险因素.结论 颈围与脐动脉Vs/Vd比值密切相关,提示肥胖与胎盘功能异常有关,即使在健康妊娠女性.