超声引导下经皮介入治疗肝脓肿对患者肝功能的影响研究

摘要

Objective To investigate the effects of ultrasound-guided percutaneous intervention on liver function of patients with liver abscess.Methods A total of 104 patients with liver abscess who were diagnosed and treated in our hospital from June 2014 to June 2016 were enrolled in the study.According to sortition method,these patients were divided into control group and research group,with 52 patients in each group.The patients in control group were treated by traditional abscess incision and drainage,however,the patients in research group were treated by ultrasound-guided percutaneous intervention.The patient's body temperature,extubation time,length of staying in hospital,liver function,blood routine test indexes and complications before and after treatment were observed and compared between two groups.Results The body temperature recovery,extubation time,length of staying in hospital in research group were superior to those in control group (P ＜ 0.05).The levels of total bilirubin (TBIL),aspertate aminotransferase (ASH) and alanine transaminase (ALT) in research group were significantly lower than those in control group (P ＜ 0.05).The white blood cell count and neutrophil count in research group were significantly lower than those in control group (P ＜ 0.05).Moreover the incidence rate of complications in research group was significantly lower than that in control group (P ＜ 0.05).Conclusion The ultrasound-guided percutaneous intervention in treatment of liver abscess can improve the liver function of patients,which is beneficial to the recovery of blood routine indexes,moreover,which can decrease the incidence of complicatins.%目的 探讨超声引导下经皮介入治疗肝脓肿对患者肝功能的影响.方法 选择2014年6月至2016年6月诊治的肝脓肿患者104例,按照抽签法分为对照组与研究组,每组52例.对照组采用传统脓肿切开引流治疗,研究组采用超声引导下经皮介入治疗,比较2组体温恢复、拔管及住院时间,治疗前后肝功能、血常规及并发症.结果 研究组体温恢复、拔管及住院时间均优于对照组,差异有统计学意义(P＜0.05).研究组总胆红素(TBIL)、天冬氨酸氨基转移酶(ASH)和丙氨酸氨基转移酶(ALT)低于对照组[(17.25±2.11) μmol/L、(63.78±7.96)U/L、(43.22±5.41) U/L比(25.30±3.16) μmol/L、(75.20±9.41)U/L、(57.81±7.23) U/L(P ＜0.05)].研究组白细胞计数、中性粒细胞计数低于对照组[(8.11±1.05)×109/L、(51.75±6.43)×109/L比(9.86±1.22)×109/L、(57.20±7.12)×109/L(P＜0.05)].研究组并发症率低于对照组(19.23％比5.76％)(P＜0.05).结论 肝脓肿患者采用超声引导下经皮介入治疗能够改善肝功能,利于血常规的恢复,且可减少并发症.