米非司酮联合米索前列醇用于终止早期妊娠和治疗稽留流产的效果比较

摘要

目的：探讨并比较米非司酮联合米索前列腺醇用于终止早期妊娠和治疗稽留流产的效果和安全性。方法：选择2008年5月至2013年5月于我院就诊的孕10～16周要求终止妊娠和稽留流产病例为研究对象，分为早期妊娠组和稽留流产组，两组患者均给予同剂量的米非司酮和米索前列腺醇序贯治疗，观察和比较两组患者的流产效果以及不良反应。结果：稽留流产组患者的完全流产率低于早期妊娠组，胎体排出后24h阴道出血量多于早期妊娠组，差异有统计学意义（P＜0.05），但两组患者口服米索前列腺醇到胎体排出的时间间隔及不良反应差异无统计学意义（P＞0.05）。结论：米非司酮联合米索前列腺醇用于治疗稽留流产效果和安全性值得肯定。%Objective: To explore and compare the effect and safety of mifepristone and misoprostol for early labor induction and missed abortion. Methods:Cases of early labor induction and missed abortion during 10-16 weeks of pregnancy in May 2008 to May 2013 in our hospital were taken as study objects and divided into two groups. The same dose of mifepristone and misoprostol were given to the cases of two groups, the effect and safety of two groups were observed. Results:Complete abortion rate of missed abortion was significant lower, and amount of bleeding were significant higher than early labor induction(P<0.05). Conclusion: The effect and safety of mifepristone and misoprostol for missed abortion were satisfactory.