子宫颈环形电切术在宫颈上皮内瘤样病变诊治中的应用

摘要

目的：探讨子宫颈环形电切术（ Loop electrosurgical excision procedure ，LEEP）在宫颈上皮内瘤样病变（ Cervical intraepithelial neoplasia ，CIN）诊治中的应用。方法对72例阴道镜下活检为CINⅠ～Ⅲ级及36例可疑CIN患者进行LEEP术治疗，随访观察各组临床效果及并发症发生情况。结果108例患者术后出血量为（22．5±4．5）ml，创面愈合时间为（6．8±2．3）周；CINⅠ～Ⅲ级组、可疑CIN组治愈率分别为95．83％、94．44％，两组治愈率比较差异无统计学意义（P＞0．05）；术后并发症发生率为20．37％；术后病理学检查与术前诊断符合率为91．67％。结论LEEP术适用于CIN及宫颈细胞学与阴道镜检查不一致、无法排除浸润癌、病理学检查异常的可疑CIN患者的治疗，手术时间短、出血量少，术后并发症少。%Objective To understand loop electrosurgical excision procedure in the diagnosis and treatment of cervical intraepithelial neoplasia .Method 72 cases of coolposcopy and biopsy as CIN Ⅰ ~III grade CIN and 36 patients suspected of CIN were treated with LEEP and observed for clinical effects and complications .Findings Postoperative blood loss was (22.5 ±4.5) ml;the wound healing time was (6.8 ±2.3) weeks;cure rates of the CINⅠ~Ⅲlevel group and the group suspicious of CIN was 95.83%and 94.44%respectively.The difference of cure rate between the two groups was not statistically significant (P>0.05);postoperative complication rate was 20.37%.Conclusion LEEP surgery can be an effective treatment for CIN and cervical cytology where colposcopy is inconsistent , invasive can not be excluded , and pathology abnormalities are found of patients suspected of CIN .It ensures shorter operative time , less blood loss, and fewer complications.