非小细胞肺癌患者疾病治疗偏好与意愿支付研究

摘要

从上海、广州抽取样本医院,通过离散选择实验问卷的形式调查了非小细胞肺癌患者人群疾病治疗偏好资料,使用效应编码对不同属性及其水平进行编码,采用随机参数Logit模型进行资料分析,研究非小细胞肺癌患者对不同治疗结局的权衡偏好以及意愿支付.结果显示:患者对不同治疗结局属性偏好权重和相对重要程度排序依次为无进展生存期、乏力疲倦、给药方式、疾病控制率、恶心呕吐、皮疹;意愿支付方面,为获得11个月的无进展生存期,患者每个月愿意支付14 400元.可见,疗效是患者治疗选择首先考虑的因素,其次是治疗副作用,给药方式在影响患者治疗选择中占有一定地位.%This study,by discrete selection experimental questionnaires,collected data of patients' disease treatment preference with non－small cell lung cancer from sample hospitals located in Shanghai and Guangzhou.After encoding patients'attributes and levels accord－ingly,the random parameter Logit model was used for data analysis.This paper explored the trade－off preferences and willingness to pay for different treatment outcomes in patients with non－small cell lung cancer. The results showed that the patient's preference weight and rela－tive importance in different treatment outcomes were ranked as following:progression－free survival,fatigue,method of drug administration, disease control rate,nausea and vomiting,rash,and patients' willingness to pay 14 400 RMB per month for 11 months of progression－free survival. It can be seen that the curative effect is the first consideration for the treatment choice of patients,followed by the side effects of treatment,and the method of drug administration plays a certain role in influencing the treatment options of patients.