兰索拉唑与奥美拉唑治疗胃食管反流病的比较观察

摘要

目的比较兰索拉唑与奥美拉唑治疗胃食管反流病的疗效.方法 将我院2010年1月至2011年6月确诊为胃食管反流病的98名患者随机分为兰索拉唑组和奥美拉唑组,分别服用兰索拉唑30mg/日 ,奥美拉唑20mg/日,疗程4周,疗程结束后比较症状与胃镜检查结果.结果 兰索拉唑组的有效率为95.92%,奥美拉唑组的有效率为79.59%,通过χ2检验,两组有显著性差异,P<0.01.结论 兰索拉唑对胃食管反流病的疗效优于奥美拉唑.%　　Objective Lansoprazole is compared with omeprazole treatment of gastroesophageal reflux disease. Methods 98 patients who diagnosed with gastroesophageal reflux in our hospital from January 2010-June 2011 were randomized into lansoprazole group and omeprazole group, respectively take 30 mg/day lansoprazole and omeprazole 20 mg/day, four weeks of treatment, symptoms after treatment compared with gastroscope inspection results. Results Lansoprazole was the effective rate of 95.92%, omeprazole group of effective rate of 79.59%, through the chi-square test, a significant difference between the two groups, P<0.01. Conclusion Lansoprazole was gastroesophageal reflux disease better therapeutic omeprazole.