骨科手术中应用瑞芬太尼复合丙泊酚全静脉麻醉的临床疗效探析

摘要

Objective To investigate the remifentanil and propofol analyze the efficacy and safety of clinical application of intravenous anesthesia in surgery applications. Methods From January 2009 to January 2012 in our hospital 300 cases of orthopedic surgery patients, randomly divided into observation group and a control group of 150 cases, the anesthetic effect of the two groups were compared, the observation group of propofol and remifentanil anesthesia control group recorded adverse reactions, and dosage of propofol with propofol and fentanyl. Results Observation group anesthesia excellent rate should be higher than that in the control group, the observation group, the dose of propofol during anesthesia is less than the control group. Observed in patients after induction of anesthesia throughout the procedure, compared to SBP and DBP values with the control group is significantly lower, the difference was significant. Observation group in the induction of anesthesia and throughout the procedure, DBP and SBP values were significantly decreased compared with before the induction of anesthesia, the difference is more obvious. Conclusion Remifentanil and propofol for total intravenous anesthesia clinical orthopedic surgery better effect, the surgery is safe and effective, and therefore should be promoted.%　　目的探讨在手术中应用瑞芬太尼复合丙泊酚进行全静脉麻醉手术的临床应用效果以及安全性比较分析。方法选择2009年1月至2012年1月期间在我院进行骨科手术的患者300例，将其随机的分为观察组和对照组各150例，比较两组患者的麻醉效果，观察组采用丙泊酚复合瑞芬太尼的方式进行麻醉，对照组采用丙泊酚复合芬太尼记录其不良反应以及丙泊酚的用量。结果观察组麻醉的优良率也要高于对照组，麻醉过程观察组的丙泊酚用量少于对照组。观察组患者在麻醉诱导后，整个手术过程中，SBP及DBP值与对照组相比明显偏低，两组比较差异显著。观察组在麻醉诱导下以及整个手术过程中，DBP以及SBP值均有明显下降，与麻醉诱导前相比，差异较为明显。结论瑞芬太尼复合丙泊酚用于全静脉麻醉的临床骨科手术中疗效较好，手术安全有效，因而应该加以推广。