埃索美拉唑与奥美拉唑治疗68例胃溃疡的临床疗效分析

摘要

Objective To analyze the omeprazole and esomeprazole the clinical therapeutic effect of gastric ulcer patients, drug adverse reactions, etc. Methods From August 2012 to September 2013 68 patients of gastric ulcer by random number method is divided into the control group, 34 cases, the experimental group, 34 cases, two groups of patients were routine treatment, the experimental group on the basis of routine therapy in patients with combined esomeprazole drug treatment, while the control group patients on the basis of conventional treatment combined omeprazole drug treatment, compared two groups of patients with the clinical symptoms improved and the occurrence of adverse drug reactions. Results Through the clinical drug treatment, the symptoms of two groups of patients with ulcer has improved to some extent, but the clinical total effective rate of experimental ulcer patients is significantly higher than the control group, and the incidence of adverse reaction is lower than the control group, significant difference between the two groups, the difference is statistically significant, P<0.05. Conclusion In many treatment of gastric ulcer, omeprazole, esomeprazole are common, but the esomeprazole treatment effect is better than that of omeprazole, and less adverse reactions, mild side effects, is safe, economic and efficient ulcer treatments.%目的：分析研究奥美拉唑以及埃索美拉唑对胃溃疡患者的临床治疗效果、药物所产生的不良反应等。方法将我院于2012年8月至2013年9月所收治68例胃溃疡患者按随机数字法分为对照组34例，实验组34例，两组患者均进行常规治疗，实验组患者在常规治疗的基础上联合埃索美拉唑药物进行治疗，对照组患者则在常规治疗的基础上联合奥美拉唑药物进行治疗，分析比较两组患者各项临床症状改善情况以及药物不良反应的发生情况等。结果经过临床药物治疗，两组溃疡患者的症状均有了一定改善，但实验组溃疡患者的临床总有效率明显高于对照组，且不良反应的发生率低于对照组，两组间差异明显，差异具有统计学意义，P<0.05。结论在胃溃疡的诸多治疗药物中，奥美拉唑、埃索美拉唑比较常见，但埃索美拉唑所取得的治疗效果优于奥美拉唑，且不良反应少，是安全、经济有效的溃疡治疗药物。