糖耐量异常患者糖化血红蛋白、血清尿酸水平改变意义的分析

摘要

目的：探讨糖耐量异常患者糖化血红蛋白（HbA1c）及血清尿酸（UA）水平变化及临床意义。方法以62例糖耐量异常患者及40例健康体检者为研究对象，对其体内HbA1c和血清UA水平进行检测与分析。结果糖耐量异常组患者FBG、2hPBG等血糖指标水平及HbA1c、血清UA水平均显著高于对照组，差异均具有统计学意义（P<0.05）；糖耐量异常患者HbA1c与血清UA水平的相关性回归分析表明， HbA1c与血清UA水平呈显著正相关（P<0.05）。结论检测糖耐量异常患者体内HbA1c和血清UA水平对糖耐量异常的诊疗具有重要的临床意义。%Objective To explore the clinical significance of detecting the levels of glycosylated hemoglobin and uric acid in patients with impaired glucose tolerance (IGT). Methods 62 patients with IGT in IGT group and 40 healthy volunteers in control group were as the research objects, the levels of glycosylated hemoglobin and uric acid were detected and analyzed. Results The levels of FBG, 2hPBG, glycosylated hemoglobin and uric acid of patients in the IGT group were signiifcantly higher than those of healthy volunteers in the control group, the differences were statistically signiifcant (P<0.05), and the levels of glycosylated hemoglobin was positively correlated with the serum level of uric acid (P<0.05). Conclusion The detection of levels of glycosylated hemoglobin and uric acid has important clinical signiifcance in patients with IGT in the diagnosis and treatment.