非球面AcrySof IQ人工晶状体植入术后视觉质量临床研究

摘要

目的 评价非球面人工晶状体(IOL)AcrySof IQ IOL植入术后年龄相关性白内障患者的视觉质量.方法 年龄相关性白内障患者42例55眼,按随机数字表法将患者分成两组.其中非球面人工晶体组24例(28眼),植入AcrySof IQ IOL;球面人工晶体组18例(27眼),植入AcrySof Natural IOL.术后随访3个月的裸眼视力(UCVA)、最佳矫正远视力(BCVA),不同亮度环境下的对比敏感度等.结果 手术后3个月非球面组UCVA为0.76±0.18,优于球面组的0.66±0.17,差异有统计学意义(P＜0.05).非球面组BCVA为0.85±0.19,优于球面组的0.74±0.19,差异有统计学意义(P＜0.05).两组球镜、柱镜差异无统计学意义(P＞0.05).在明视觉条件下,非球面组在12.0 cpd、18.0 cpd的对比敏感度明显优于球面组(P＜0.01).在暗视觉条件下非球面组所有空间频率的对比敏感度非球面组均优于球面组(P＜0.05).非球面组眩光、光晕等的发生率均低于球面组(P＜0.05).结论 白内障术后早期,非球面人工晶状体能够提供较好的术后裸眼视力、最佳矫正远视力、亮环境下高频对比敏感度和暗环境下的所有空间频率的对比敏感度,提示非球面人工晶状体能够提供较好的视觉质量.%Objective To evaluate the visual quality of eyes implanted with AcrySof IQ aspherical intraocular lenses( IOLs ). Methods Forty-two patients( 55 eyes ) with age-related cataracts were enrolled in the study, who were randomly divided into two groups according to random number table. Phacoemulsification and IOL implantation were applied to patients with aspherical IOLs( AcrySof IQ ) in 28 eyes and spherical IOLs( AcrySof Natural IOL ) in 27 eyes, respectively. All patients were followed up for 3 months. The examinations included uncorrected visual acuity ( UCVA ),best corrected visual acuityC BCVA ),contrast sensitivity( Functional Acuity Contrast Test ),and questionnaires were applied on the 3rd month after operation. Results UCVA( aspherical/spherical: 0.76 ± 0.18/0.66 ± 0.17 ) and BCVA( aspherical/spherical :0.85 ± 0.19/0.74 ± 0.19 ) were significantly better in eyes with aspherical IOLs than in those with spherical IOLs( P < 0.05 ). There was no significant difference in spherical lens value or column lens value between the two groups( P >0.05 ). Higher contrast sensitivity values under photopic condition( 12.0 cpd,18.0 cpd ) and under mesopic conditon( 1.5 cpd,3.0 cpd,6.0 cpd, 12.0 cpd, 18.0 cpd ) were also found in aspherical IOLs group ( P <0.05 in each condition ). The visual disturbances were less in the aspherical IOLs group( P <0.05 ). Conclusion The aspherical IOLs provides better UCVA, BCVA and contrast sensitivity under photopic and mesopic conditions for the patients with cataract at the early postoperative stage,thus improves the optical quality.