南宁市肠易激综合征患者症状诱发因素的调查

摘要

目的：探讨广西南宁市肠易激综合征（ IBS）患者症状发作或加重的诱发因素。方法采用整群、分层、随机抽样方法，抽取南宁市5个城区18～80岁人群2773例进行问卷调查，了解人群中IBS患病情况，并对可能影响IBS患者症状发作或加重的相关因素进行单因素及多因素logistic非条件回归分析。结果根据IBS罗马Ⅲ诊断标准，2773例被调查者中，诊断为IBS 181例（IBS组），非IBS 2592例（非IBS组）；整体人群患病率为6．53％，每例患者有（3．31±2．29）个诱发因素。单因素分析结果显示：进食生冷食物、辛辣食物、乳制品、水果、饮酒及受凉、情绪不佳、劳累是IBS患者症状的发作或加重的单危险因素（P＜0．05）。多因素logistic非条件回归分析结果显示：进食生冷食物、水果、乳制品及情绪不佳是IBS患者症状发作或加重的独立危险因素（P＜0．05）。结论进食生冷食物、水果、乳制品及情绪不佳是南宁市IBS患者症状发作或加重的独立危险因素。%Objective To investigate the precipitating factors for onset and exacerbation of syndrome in patients with irritable bowel syndrome( IBS) in Nanning,Guangxi.Methods A questionnaire survey on IBS was conducted among 2 773 residents aged 18-80 years from five districts of Nanning using the method of stratified cluster random sampling.Univariate analysis and multivariate unconditional logistic regression analysis were used to analyze the related influence factors of onset or exacerbation of IBS.Results According to the RomeⅢdiagnostic criteria for IBS,181 of 2 773 subjects were diagnosed with IBS( IBS group) and 2 592 without IBS( non-IBS group) . The overall prevalence rate of IBS was 6.53%,with(3.31 ±2.29) precipitating factors per patient.Univariate analysis revealed raw and cold foods,spicy foods,dairy products,fruits,alcohol intake and catching a cold,poor mood,and fatigue were the single risk factors for onset or exacerbation of IBS(P<0.05).Multivariate unconditional logistic regression analysis revealed raw and cold foods,fruits,dairy products,and poor mood were the independent risk factors for onset or exacerbation of IBS(P<0.05).Conclusion Raw and cold food, fruits,dairy products,and poor mood are the independent risk factors for onset or exacerbation of IBS in Nanning.