心血管手术输血后庚型肝炎病毒感染与年龄的关系

摘要

Objective To investigate the correlation between age and Hepatitis G Virus(HGV) infection after blood transfusion in patients undergoing cardiovascular operation. Methods A prospective study was performed on 166 patients undergoing cardiovascular operation. Hepatitis G Virus RNA (HGV RNA) was tested preoperatively and 1,2,3 month postoperatively. The patients were divided into older group ( ≥36 years of age) and younger group(<36 years of age). Results The overall postoperative morbidity of HGV infection was 4.2%. There was a higher positive expression for HGV in the older group than the younger group. Significant differences were found in the weight, the volume of blood transfusion and the causes of diseases between the two groups. Conclusion The overall postoperative morbidity of HGV infection was 4.2 %. The elder patients were more susceptible to HGV than young patients. The result indicates that cardiovascular operation should be done early.%目的探讨心血管手术输血后庚型肝炎病毒(HGV)感染与年龄的关系。方法选取连续166例心血管手术患者进行前瞻性研究，按年龄分为A，B两组，≥36岁为A组，<36岁为B组，测定手术前后血样标本的庚型肝炎病毒RNA(HGV RNA)。结果术后3个月HGV总感染率4.2％。A组较B组感染率高(P=0.0064)，体重大(P<0.0001)，输血量多(P<.0001)，B组以先天性心脏病为主(P<0.0001)。结论心血管手术输血后HGV感染率为4.2％。小儿和青壮年感染率较中老年人低。提示心血管手术应早期施行。