Objective To investigate the correlation between the National Institutes of Health Chronic Prostatitis Symptom Index ( NIH-CPSI) and quantity of leukocytes and small particles of lecithin ( SPL) in expressed prostatic se-cretion ( EPS) in CategoriesⅢA,ⅢB and Ⅳprostatitis.Methods EPS samples were collected from 183 patients who came to Department of Andrology and Sexual Medicine, diagnosed with Categories ⅢA,ⅢB or Ⅳ prostatitis.Each sub-ject filled out NIH-CPSI questionnaire, and the amount of leukocytes and SPL in EPS was measured.Correlation between NIH-CPSI and the amount of leukocyte and SPL in EPS in CategoriesⅢA,ⅢB andⅣprostatitis was analyzed.Results There was no rank correlation between NIH-CPSI and the amount of leukocyte and SPL in EPS in Category ⅢA pa-tients (P>0.05).There was no rank correlation between leukocyte count and the amount of SPL in CategoryⅢA patients (P>0.05).There was no rank correlation between NIH-CPSI and the amount of SPL in EPS in Category ⅢB patients (P>0.05).There was no rank correlation between the amount of leukocyte and the amount of SPL in EPS in CategoryⅣpatients ( P>0.05) .Conclusion There was no evident correlation between symptom severity and the amount of leuko-cytes and SPL in EPS in different categories of prostatitis.It is not reliable to evaluate the severity of chronic prostatitis with leukocyte and SPL count.The negative effects of chronic prostatitis are mainly from the severity of symptoms.Symp-tom alleviation should be the focus in clinical diagnosis and management of the disease.%目的：探讨NIH－ⅢA、ⅢB及Ⅳ型前列腺炎患者的前列腺液中白细胞（ WBC）、卵磷脂小体（ SPL）及慢性前列腺炎症状指数（ NIH－CPSI）之间的相关性。方法收集泌尿男性科门诊183例ⅢA、ⅢB及Ⅳ型前列腺炎患者的前列腺液，患者填写NIH－CPSI量表，并测定前列腺液中WBC及SPL计数，分析不同分型前列腺炎患者CPSI评分、前列腺液WBC、SPL计数的相关性及特点。结果ⅢA型前列腺炎患者前列腺液WBC、SPL计数与CPSI量表评分均无秩相关关系（P＞0.05），并且前列腺液中WBC与SPL计数无秩相关关系（P＞0.05）；ⅢB型前列腺炎患者CPSI量表评分与SPL计数无秩相关关系（ P＞0.05），Ⅳ型前列腺炎患者前列腺液中WBC与SPL计数无秩相关关系（ P＞0.05）。结论不同分型前列腺炎患者前列腺液中WBC、SPL计数与患者症状严重程度之间无明确相关性，WBC与SPL计数用于评估慢性前列腺炎病情可靠性差，慢性前列腺炎负面影响主要源于症状，临床诊疗中应重视并改善患者症状。
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