甲基睾丸酮在罗非鱼体内的消解规律

摘要

研究了在现实养殖环境中,采用含甲基睾丸酮200 mg/kg的饲料持续投喂罗非鱼成鱼3 d,随后将其转移到养殖池塘中体内甲基睾丸酮的消解规律。应用高效液相色谱法检测不同时间肌肉和鱼皮中甲基睾丸酮的残留量,结果发现肌肉和鱼皮中甲基睾丸酮残留量趋势为指数递减,组织中甲基睾丸酮残留量在停药后1164 h,即49 d时才无检出。%Studies were conducted on the Elimination of 17a-methyltestosterone（MT） in adult Nile tilapia Oreochromis niloticus（L.） that received dietary of MT to induce growth under aquaculture model.Nile tilapia were fed on a diet containing MT（200 mg/kg） for 3 d,then transferd to a pond with normal feed.In the latter days,MT residues in muscle and skin were measured by high performance liquid chromatography（HPLC）,DAS drug dynamics software combines EXCEL 2003 statistical software were applied to the data processing and analysis in order to get the elimination rule of MT in tilapia muscle and skin.The results showed that,the elimination of MT in muscle and skin were relatively slow following the withdrawal for exponential decline,and ended approximately in 1164 h,49 d withdrawal.