水杨酸新戊二酯的合成

摘要

以水杨酸、氯化亚砜为原料,无水吡啶为催化剂,先制得水杨酰氯,再与新戊二醇在催化剂NaHSO4作用下合成了水杨酸新戊二酯,产品收率可达到89%以上,产品纯度97.6%。所得产物经GC-MS、核磁氢谱表征确认了其结构。%First,salicylaldehyde chloride is obtained by salicylic acid and thionyl chloride,anhydrous pyridine as catalyst.And then,2,2-dimethylpropane-1,3-diyl bis（2-hydroxybenzoate） is synthesized by salicylaldehyde chloride and neopentyl glycol at the role of the catalyst NaHSO4.The yield of the product can be reached more than 89 %.Purity of the product was 97.6 %.The product was characterized by GC-MS and 1HNMR,confirmed its structure.