狭瓣鹰爪花枝叶中化学成分研究

摘要

综合运用硅胶柱色谱、反相硅胶柱色谱、Sephadex LH-20凝胶柱色谱以及制备型高效液相等色谱分离技术,对番荔枝科鹰爪花属植物狭瓣鹰爪花Artabotrys hainanensis枝叶中的化学成分进行系统研究.结合理化性质和多种现代波谱技术,并通过与文献进行对照,鉴定了从狭瓣鹰爪花枝叶90 %乙醇提取物的中分离得到6个化合物,分别鉴定为:5-羟基-7,8-二甲氧基二氢黄酮(1)、litseachromolaevane A (2)、liguducin A (3)、1β-hydroxy-4(15), 5E, 10(14)-germacratriene (4)、(9E,11Z) 14-hydroxyoctadecan-9,11-dienoic acid (5)和benzyl benzoate (6).其中化合物1为黄酮类化合物,化合物2-4为倍半萜类化合物,化合物5为脂肪酸类化合物,化合物6为芳酸类化合物,所有化合物均为首次从鹰爪花属植物中分离得到.%The chemical consituents from stems and leaves of Artabotrys hainanensis were separated and purified by column chromatographies with silica gel, ODS, Sephadex LH-20 and Pre-HPLC. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic analysis, as well as comparisons with the data in literature. Six compounds were isolated and elucidated as 5-hydroxy-7,8-dimethoxyflavanone (1), litseachromolaevane A (2), liguducin A (3), 1β-hydroxy-4(15), 5E, 10(14)- germacratriene (4), (9E,11Z) 14-hydroxyoctadecan-9,11-dienoic acid (5) and benzyl benzoate(6).All compounds were isolated from the genus Artabotrys for the first time.