The plants of Flemingia Roxb. ex Rottl have been widely used as a national medicine and folk medicine in our country since antiquity, six of which have an exact and long history of medicinal use. In Traditional Chinese medicine, the plants of Flemingia Roxb. ex Rottl have the effects of dispelling wind and removing dampness from the body, strengthening the sinews and the bones, diminishing inflammation and relieving pain, stimulating the circulation of the blood and causing the muscles and joints to relax. Clinically, they can be used to treat the injuries from fall, fractures, contusions and strains, pain in the waist and lower extremities, breast diseases, toothaches and gynecological diseases, etc. Recently, scholars both home and abroad found that the plants of Flemingia Roxb. ex Rottl contain such chemical components as sugars, flavonoids, amino acids, steroids, alkaloids, and volatile oils, etc. In addition, the plants of Flemingia Roxb. ex Rottl are anti-estrogenic effect and have the effects similar to xenoestrogen. Moreover, they are anti-inflammatory, antithrombotic, antioxidative and analgesic and have protective effects on nervous system injury. In this review, we summarize the chemical components and pharmacological effects of the Flemingia Roxb. ex Rottl, derived from our analysis of high-quality studies home and abroad and review of the literature on the Flemingia Roxb. ex Rottl, in the hope of providing reference for its further study, clinical application and development of new drugs in the future.%千斤拔属植物在中国一直作为民族药及民间药被广泛使用,其中有六种有确切药用历史,在中医上此属植物具有祛风除湿、强筋壮骨、消炎止痛、舒筋活络等功效,在临床上可用于治疗跌打损伤、腰腿痛、乳房疾病、牙痛及妇科病等. 近年来国内外学者发现此属植物中含有糖类、黄酮类、氨基酸、甾体、生物碱、挥发油等其他化学成分,且具有类雌激素及抗雌激素样作用,以及良好的抗炎、抗血栓、抗氧化、镇痛、对神经系统损伤的保护等生物活性. 本文通过查阅相关文献资料,对近年来国内外所研究的千斤拔属植物的化学成分及药理作用进行综述,为此属植物进一步研究,临床应用及新药开发提供参考.
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