苄星青霉素联合皮肤物理抗菌膜治疗梅毒硬下疳的效果分析

摘要

目的：探讨分析苄星青霉素联合皮肤物理抗菌膜治疗梅毒硬下疳的效果。方法：回顾分析2013年1月至2013年7月我院治疗的96例Ⅰ期梅毒硬下疳患者，随机均分为治疗组与对照组，各48例，两组治疗均参考中国疾病防治中心制定的《性传播疾病临床诊疗治疗》中有关Ⅰ期梅毒硬下疳的青霉素治疗方法，肌肉注射苄星青霉素240万U，每周1次，疗程为1个月，治疗组在此基础上采用洁悠神治疗，在皮损处均匀喷洒洁悠神（主要成分是有机硅季铵盐活性剂），2次/d，疗程为一个月。记录治疗第5d、10d、15d、20d所有患者的病情发展情况和皮损愈合情况，并在两个疗程后复查快速血浆反应素环状卡片试验（RPR）。结果：治疗组在治疗第5d、10d、15d愈合率均少于对照组，差异均有统计学意义（P>0.05）。结论：苄星青霉素联合皮肤物理抗菌膜治疗梅毒能有效缩短硬下疳的皮损愈合时间。%Objective:To investigate the joint analysis of benzathine penicillin skin physical antimicrobial film treatment of syphilis chancre effect . Methods:A retrospective analysis from January 2013 to July 2013 in our hospital treated 96 cases of syphilis chancre Ⅰ patients were randomly divided into treatment group and control group,48 cases,and after treatment were developed with reference to the Chinese Center for Disease Control and Prevention“clinical diagnosis and treatment of sexually transmitted diseases treatment” regarding penicillin treatmentisyp hilis chancre,and intramuscular benzathine penicillin 2.4 million U,1 times a week, treatment for a month,the treatment group were JUC on this basis treatment, lesions at a uniform spray JUC(the main component of silicone quaternary active agent),2 times/d,treatment for a month. Results:Record of treatment 5d,10d,15d,20d all the patient's condition and the development of healing skin lesions,and after reviewing two courses rapid plasma reagin test(RPR). The treatment group in the treatment of the first 5d,10d,15d healing rate than the control group,he difference was statistically significant (P>0.05). Conclusion:Benzathine joint physical antimicrobial skin membrane treatment of syphilis chancre can effectively shorten the healing time of skin lesions .