目的 了解上海市闵行区婚检人群单纯疱疹病毒2型(herpes simplex virus type 2,HSV-2)感染情况及其影响因素.方法 对上海市闵行区2013-2014年的婚检人群进行艾滋病相关知识、性行为情况问卷调查.采集血样检测HIV、HSV-2及梅毒感染情况.结果 共调查2 116名婚检对象,共有92人感染HSV-2,感染率为4.35%.其中男性感染率为3.69%,女性感染率为5.01%.多因素Logistic回归分析显示,对于男性婚检人群,文化程度为高中及以下(OR=2.47,95%CI:1.195~5.108),未婚妻为HSV-2阳性(OR=9.29,95%CI:4.279~20.164)者更容易感染HSV-2.对于女性婚检人群,年龄≥25岁(OR=9.29,95%CI:4.279~20.164),非上海市户籍(OR=2.19,95%CI:1.091~4.378),文化程度为高中及以下(OR=3.37,95%CI:1.721~6.596),从不使用安全套(OR=3.45,95%CI:1.265~9.392),未婚夫为HSV-2阳性(OR=8.46,95%CI:3.700~19.351)者更容易感染HSV-2.结论 上海市闵行区婚检人群的HSV-2阳性率较低,然而安全套使用率低导致未婚夫妻中任何一方感染HSV-2就会增加另一方的感染风险,提示需进一步提高未婚夫妻安全套使用.%Objective To explore herpes simplex virus type 2 (HSV-2) infection and associated factors among people participating premarital physical examination in 2013-2014 in Minhang District of Shanghai.Methods During 2013 to 2014,people participating premarital physical examination in Minhang District were interviewed with questionnaire regarding HIV/AIDS related Knowledge,sexual behaviors,etc.Blood samples were collected to detect HIV,HSV-2 and syphilis.Results A total of 2 116 participants were investigated,among which 92 were infected with HSV-2,with a prevalence rate of 4.35%.The HSV-2 infection rates were 3.69% and 5.01% for male and female,respectively.Multivariate logistic regression analysis showed that for the males,education level of high school and below (OR=2.47,95%CI:1.195-5.108),fiancee infected with HSV-2 (OR=9.29,95%CI:4.279-20.164) were more susceptible to HSV-2.For the females,aged above 25 years (OR=9.29,95%CI:4.279-20.164),census register of other cities in China (OR =2.19,95%CI:1.091-4.378),education level of high school and below (OR =3.37,95%CI:1.721-6.596),never used condoms (OR =3.45,95%CI:1.265-9.392),fiance infected with HSV-2 (OR =8.46,95%CI:3.700-19.351) were more susceptible to HSV-2.Conclusions The prevalence of HSV-2 among premarital population is relatively low in Minhang District.However,low condom use rate leads to an increase in the risk of HSV-2 infection when either partner infected with HSV-2,suggesting increasing condom use between affianced couples.
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