N,N-二烯丙基-5-甲氧基色胺片剂的GC/MS检验

摘要

Objective To establish a method for identification of N,N-diallyl-5-methoxytryptamine by GC/MS. Methods The sample was extracted with methanol in ultrasonic bath. And the supernatant was injected into GC/MS. Results Unknown component (tR=10.45min) presented characteristic fragment ion peaks at m/z 110.1 (base peak), 270.1, 174.1, 160.1, 145.0, 130.1 and 117.1. According to relevant literatures and mass spectrometry analysis, this drug was identified as N,N-diallyl-5-methoxytryptamine. This compound belonged to tryptamines. Conclusions Method established in this paper is simple, accurate, and suitable for identification of N,N-diallyl-5-methoxytryptamine.%目的：建立 N,N-二烯丙基-5-甲氧基色胺的气相色谱-质谱(GC/MS)定性分析方法。方法未知片剂样品用甲醇超声溶解，吸取上清液采用气相色谱-质谱（GC/MS）联用仪检测。结果测得未知组分（tR=10.45min）的质谱特征碎片峰（m/z）信息为110.1（基峰）、270.1、174.1、160.1、145.0、130.1和117.1。查阅资料并对该组分的质谱图谱进行解析，鉴定为 N,N-二烯丙基-5-甲氧基色胺，属于色胺类化合物。结论该方法简单，准确，可用于 N,N-二烯丙基-5-甲氧基色胺的鉴定。