目的:探讨右美托咪定用于臂丛神经阻滞麻醉上肢手术的效果及对患者认知功能的影响.方法:选取2015年7月—2017年7月江西省分宜县中医院收治的拟行臂丛神经阻滞麻醉上肢手术患者80例,以随机数字表法分为观察组和对照组,每组40例.对照组患者给予罗哌卡因联合利多卡因进行麻醉,观察组患者在对照组基础上加用右美托咪定.比较两组患者麻醉前后心率、平均动脉压,运动、感觉神经阻滞起效时间及维持时间和认知功能评分变化情况.结果:麻醉后40 min,两组患者心率、平均动脉压明显低于麻醉前10 min,但观察组患者明显高于对照组,差异均有统计学意义(P0.05);观察组患者运动、感觉神经阻滞维持时间明显长于对照组,差异均有统计学意义(P0.05);术后0.5、24 h,观察组患者认知功能评分明显高于对照组,差异均有统计学意义(P0.05 ); the maintenance time of motor nerve blocking and sensory nerve blocking of the observation group was significantly longer than those of control group , with statistically significant difference (P0.05).At 0.5 h and 24 h after anesthesia, score of cognitive function of observation group was significantly higher than that of the control group , with statistically significant difference (P<0.05).CONCLUSIONS:The anesthesia effect of dexmedetomidine in brachial plexus block anesthesia of upper limb surgery is remarkable , which can significantly promote the recovery of patients ' cognitive function .
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