目的：对比来曲唑与氯米芬促排卵治疗多囊卵巢综合征临床效果。方法收集60例多囊卵巢综合征患者，行促排卵治疗前均服用炔雌醇环丙孕酮片调整内分泌，对照组在此基础上采取氯米芬治疗，观察组则用来曲唑进行治疗，治疗结束后统计组间促排卵效果并实施比较。结果观察组患者的子宫内膜厚度较对照组明显增厚，有优势卵泡数、排卵率及妊娠率较对照组显著增加，卵巢过度刺激综合征（OHSS）发生率较对照组更低，组间比较差异有统计学意义（P＜0.05）。结论来曲唑较氯米芬在促排卵治疗多囊卵巢综合征效果更优，临床妊娠率高，且减少子宫内膜变薄、OHSS的发生风险，可作为一线促排卵药物。%Objective To compare letrozole and clomiphene citrate ovulation treatment of polycystic ovary syndromeclinical effect. Methods 60 cases of patients with polycystic ovary syndrome, for ovulation induction therapy beforetaking the British adjust the endocrine, the control group on the basis of taking clomip hene treatment, the observation group used letrozole treatment, after treatment between statistical group ovula tion effect and carry out comparative. Results In the observation of the endometrial thickness group than the control group in the markedly thickened, with the number of dominant follicle, ovulation rate and pregnancy rate increased signiifcantly compared with the control group, the incidence rate of OHSS is lower than control group, there were statistically signiifcantdifferences between groups(P<0.05). Conclusion Letrozole than cl omiphene in ovulation promoting syndrome better effect in treating polycystic ovary, clinical pregnancy rate is high, the risk is reduced and the thin the lining of the uterus, ovarian hyperstimulation syndrome, can be used as a ifrst-line treatment for induction of ovulation.
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