Objective To understand the current status of hepatitis B virus (HBV) infection among the healthy population in Tianjin. Methods The survey of HBV infection status and hepatitis B vaccination was conducted among the healthy population selected in 16 counties (district) in Tianjin with stratified cluster random sampling. Results The results showed that the positive rates of HBsAg, anti-HBs and anti-HBc were 2.63%, 47.63% and 10.15% respectively. The positive rate of HBsAg was significantly higher in males (3. 52% ) than in females ( 1. 73% ) and increased with age (x2 = 30. 39, P < 0. 05); The positive rate of HBsAg varied with areas, which was highest in coastal area (4. 17 % ) and lowest in urban area (1. 85 % ), the difference was statistical significant (x2 = 9. 59, P < 0. 05). The positive rate of HBsAg was highest in farmers (4.44% ) and lowest in children aged < 10 years (0. 38% ). The positive rates of anti-HBs were similar between males and females, which declined with age. Conclusion The new sampling method was suitable for the serological surveillance of hepatitis B in the context of the difficulty existing in household survey for collecting blood sample and the result of the study was representative.%目的 了解2010年天津市不同年龄段的健康人群乙型病毒性肝炎(乙肝)病毒(HBV)感染或免疫状况.方法 根据年龄段和职业,在全市16个区(县)中采取分层整群随机抽样方法确定目标人群,对目标人群采用统一的调查表,调查登记与HBV感染和乙肝疫苗免疫相关的信息.结果 1～59岁健康人群HBV表面抗原(HBsAg)、表面抗体(抗-HBs)和核心抗体阳性率分别为2.63％、47.63％和10.15％；HBsAg阳性率:男性3.52％、女性1.73％,差异有统计学意义(x2 =13.78,P＜0.05),且随年龄的增长而逐渐升高,差异有统计学意义(x2=30.39,P＜0.05)；滨海三区最高(4.17％),市内六区最低(1.85％),地区间差异有统计学意义(x2 =9.59,P＜0.05)；农民最高(4.44％),＜10岁儿童最低(0.38％).抗-HBs阳性率:男性与女性基本一致,且随年龄的增长而显著降低,差异有统计学意义(x2 =302.06,P＜0.05).结论 新抽样方法适于现时期入户采血难的形势,且研究结果同样具有代表性.
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