Objective To observe the effect of surgical treatment for acute cholecystitis with diabetes mellitus. Methods Ran-domly selected in our hospital in recent years treated 20 cases of diabetes mellitus complicated with acute cholecystitis pa-tients (Study Group) and treated in the same period of 20 cases of non-diabetic acute cholecystitis patients (control group) as the research object, the two groups of patients given the same treatment were compared between the two groups of treat-ment effect. Results The results showed that group of 20 patients in the study, infection of incision, internal biliary infection, arrhythmia and electrolyte disturbance occurrence rate was 40.00%, 10.00% and 20.00% and 20.00%; in the control group of 20 patients, incision infection, internal biliary infection, arrhythmia, and hydropower solution quality disorder incidence is 10.00%, 10.00%), 15.00%and 20.00%, in addition to the incision infection occurred between the rate difference has statis-tical significance (χ2=4.80, P<0.05), others are not statistically significant (P>0.05). From the pathological type, the group of 20 patients in the study, 2 patients for acute cholecystitis (10.00%), 11 patients for acute suppurative cholecystitis (55.00%), 7 patients for acute gangrenous cholecystitis (35.00%);in the control group of 20 patients, 4 cases of patients with simple of gallbladder inflammation (20.00%), 14 patients for acute suppurative cholecystitis (70.00%) and 2 patients for acute gan-grenous cholecystitis (10.00%), the difference between the two groups of patients with pathological type proportion no statis-tical significance (χ2=3.80, P>0.05). Conclusion Diabetes mellitus should not be the obstacle of surgical treatment for pa-tients with acute cholecystitis. Should be treated as soon as possible the patients, preoperative carefully check the important organs have no visible lesions, detection of related organs function, accurate adjustment of insulin dosage to ensure periop-erative blood glucose stability, is the key to the success of the operation.%目的：观察急性胆囊炎是否合并糖尿病患者手术治疗效果。方法随机选择该院近年来收治的20例合并糖尿病的急性胆囊炎患者(研究组)和同期收治的20例未合并糖尿病的急性胆囊炎患者(对照组)为研究对象，两组患者给予同样的治疗方法，比较两组患者的治疗效果。结果该研究结果显示，研究组20例患者中，切口感染、胆内感染、心律失常和水电解质紊乱发生率分别为40.00%、10.00%、20.00%和20.00%；对照组20例患者中，切口感染、胆内感染、心律失常和水电解质紊乱发生率分别为10.00%、10.00%、20.00%和15.00%，除切口感染发生率之间的差异具有统计学意义(χ2=4.80，P<0.05)外，其它差异均无统计学意义(P均>0.05)。从病理类型看，研究组20例患者中，2例患者为急性单纯性胆囊炎(10.00%)，11例患者为急性化脓性胆囊炎(55.00%)，7例患者为急性坏疽性胆囊炎(35.00%)；对照组20例患者中，4例患者为单纯性胆囊炎(20.00%)，14例患者为急性化脓性胆囊炎(70.00%)，2例患者为急性坏疽性胆囊炎(10.00%)，两组患者病理类型比例之间差异无统计学意义(χ2=3.80，P>0.05)。结论糖尿病不应为急性胆囊炎患者手术治疗的障碍所在。应及早治疗该类患者，术前认真检查重要脏器有无明显病变，检测相关脏器的功能，准确调整胰岛素的用量，保证围术期血糖稳定是手术成功的关键所在。
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