Induced-pluripotent stem cells seeded acellular peripheral nerve graft as “autologous nerve graft”

摘要

The hypothesis is that induced pluripotent stem cells (iPSC) derived Schwann cells and/or macrophages can be transplanted into acellular nerve graft in repairing injured nervous system. The efficiency of iPSC seeded acellular nerve graft may mimic the autologous peripheral nerve graft.