Genomes are dynamic entities that evolve over time where the cumulative effects of small-scale sequence alterations caused by mutation play an important role. Mutations result either from errors in DNA replication or from the damaging effects of mutagens such as chemicals and radiation that react with DNA and change
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机译:Influential factor contributing to the isoform-specific inhibition by aTp of human mitochondrial NaD(p)(+)-dependent malic enzyme - Functional roles of the nucleotide binding site Lys346