Knowledge sharing has become an important issue that challenges the efficient healthcare delivery in eHealth system. It also rises as one of the most demanding applications with reference to dynamic interactivities among various healthcare actors (e.g. doctors, nurses, patients, relatives of patients). In this paper, we suggest an activity theory based ontology model to represent various healthcare actors. The goal of the suggested model is to enhance interactivities among these healthcare actors for conducting more efficient knowledge sharing, which helps to design eHealth system. To validate the feasibility of suggested ontology model, three typical use cases are further studied. A questionnaire based survey is carried out and the corresponding survey results are reported, together with the detailed discussions.
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