Proteinaceous infectious particles(prions) are unique pathogens as they are devoid of any coding nucleic acid.Whilst it is assumed that prion disease is transmitted by a misfolded isoform of the cellular prion protein, the structural insight of prions is still vague and research for high resolution structural information of prions is still ongoing. In this review, techniques that may contribute to the clarification of the conformation of prions are presented and discussed.
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机译:Etude preliminaire sur l'Utilization de Techniques de Techniques de Demodulation de phase pourl'analyse des Donnees Vibratoires des Engrenages(使用相位解调技术分析齿轮振动数据的初步研究)