Until recently,stress hyperglycemia was considered to be a beneficial adaptive response,with raised blood glucose providing a ready source of fuel for the brain,skeletal muscle,heart and other vital organs at a time of increased metabolic demand.Following the Leuven Intensive Insulin Therapy Trial in 2001,tight glycemic control became rapidly adopted as the standard of care in intensive care units(ICU's) throughout the world.However,four randomized controlled studies and the recently published NICE-SUGAR study have subsequently been unable to replicate the fi ndings of the Leuven Intensive Insulin Therapy Trial.This paper offers an explanation for these discordant f indings,and provides a practical approach to glucose control in the ICU.
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机译:Impact of Glycemic Control on the Clinical Outcome in Diabetic Patients With Percutaneous Coronary Intervention :一from the FU-Registry-日本循环器学会Late Breaking Clinical Triall-5 (2011年8月)
机译:Impact of Glycemic Control on the Clinical Outcome in Diabetic Patients With Percutaneous Coronary Intervention :一from the FU-Registry-日本循环器学会Late Breaking Clinical Triall-5 (2011年8月)
机译:Histological course of nonalcoholic fatty liver disease in Japanese patients: Tight glycemic control, rather than weight reduction, ameliorates liver fibrosis