Establishment of a non-lethal model of antibody-dependent enhancement of infection in A129 mice based on a non-mouse-adapted dengue virus strain

摘要

DEAR EDITOR,Dengue fever(DF),caused by dengue virus(DENV)infection,is a highly prevalent mosquito-borne infectious disease.The development of antiviral drugs and vaccines relies on the clinical utility of dengue infection models,particularly those involving antibody-dependent enhancement(ADE).