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《分子与细胞生物力学(英文)》
>Computational Study of Anastomosis Angle of Arteriovenous Fistula forHemodialysis
Computational Study of Anastomosis Angle of Arteriovenous Fistula forHemodialysis
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Arteriovenous fistula(AVF)is the endorsed method of vascular access for hemodialysis in end-stage renal disease(ESRD).However,more than 60% of AVF fail to mature for hemodialysis.Intimal hyperplasia leads to stenosis is the primary cause of fistula failure.Wall shear stress(WSS)is one of the important parameters that enact a crucial role in building of intimal hyperplasia.The prime purpose of this research work is to investigate the effect of anastomosis angle on WSS,pressure drop,venous outflow rate and identify the optimal angle of anastomosis of AVF,so that it helps to standardize the surgical technique.In this research work,three-dimensional idealized geometries of end-to-side type AVF for the four different angles of anastomosis are created.Numerical simulation performed using incompressible,Newtonian blood to calculate the WSS,blood flow rate at the distal end of the vein and pressure drop across the anastomosis for the three arterial inflow 350,500 and 900 ml/min.For all three arterial inflow,the WSS is high at 75°compared to other angles and it is less at 60°.The WSS at 45°and 90°are moderate.The venous outflow is increasing with the increase in arterial inflow condition for all anastomosis angles except for 45°.The outflow rate at distal venous end is highest,344.85 ml/min at 45°for 500 ml/min arterial inflow.Pressure drop high at 45°and lowest at 90°.The intensity of disturbed flow and recirculation zone was observed at the area of anastomosis and it is high at 75°.From the results and observations,it can be concluded that 45°angle is the best choice for the anastomosis of AVF.This finding will standardize the surgical technique and subsequently,it will help to mature the AVF early and for a long time.
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机译:RE: The treatment timing of labial inversely impacted maxillary central incisors: A prospective study. Hao Sun, Rongdang Hu, Manman Ren, Yan Lin, Xiuying Wang, Chaofan Sun, Yi Wang. The Angle Orthodontist. 2016;86:768-774
机译:RE: The treatment timing of labial inversely impacted maxillary central incisors: A prospective study. Hao Sun, Rongdang Hu, Manman Ren, Yan Lin, Xiuying Wang, Chaofan Sun, Yi Wang. The Angle Orthodontist. 2016;86:768-774