子宫切除与子宫动脉栓塞对卵巢功能影响的对比研究

摘要

Objective To compare research for the effects of uterine resection and uterine arterial embolization on the function of ovary. Methods The serum concentrations of estrin(E2), follicule-stimulating hormone(FSH), luteotropic hormone(LH)and prolactin(PRL) were measured in 40 patients with uterine leiomyoma without operation,20 patients with uterine resection, 20 patients with uterine arterial embolization and 20 normal women.Results The serum concentrations of estrin(E2) in the group of uterine resection lower than the normal control group, there was a significant difference between them.Compare the serum concentrations of estrin(E2) in the group of uterine arterial embolization and the normal control group, there was no significant. The serum concentrations of prolactin(PRL) in the group of uterine leiomyoma was higher than the normal control group with significant difference.When the uterus was resected or uterine artery was embolished, the serum oncentrations of PRL decreased remarkably. Conclusion Uterine resection has effects on the function of ovary, but uteine arterial embolization would not.PRL may be one of the factors causing the formation of uterine leiomyoma.%目的：研究子宫切除与子宫动脉栓塞对卵巢功能影响。方法对40例子宫肌瘤患者术前、20例子宫切除术后1年、20例子宫动脉栓塞术后1年患者、20例正常人群这4组人群的妇女，检测血中E2、PRL、LH和FSH。结果子宫切除组中患者的E2较正常对照组低，两者的差异有显著性；子宫动脉栓塞后患者的E 2与正常人群的比较差异无显著性；子宫肌瘤术前患者的PRL高于正常对照组，两者比较差异有显著性，子宫切除后或子宫动脉栓塞后，血中泌乳素水平明显下降。结论子宫切除术后对卵巢功能有影响，子宫动脉栓塞后对卵巢功能无明显影响，PRL可能是子宫肌瘤发病因素之一。