目的：探讨为行妇科腔镜手术治疗的患者应用异丙酚与七氟醚进行麻醉对其术后发生恶心呕吐（PONV）情况的影响。方法：将我院收治的38例妇科腔镜手术患者分为P组（异丙酚组）和S组（七氟醚组），每组各19例患者。为P组患者在手术的全程使用异丙酚进行麻醉，为S组患者在手术中使用异丙酚进行麻醉诱导且在手术的全程使用七氟醚进行麻醉，并采用Rhodes评分对两组患者在术后1h、6h和24 h发生 PONV的情况进行评估。结果：在术后1 h， P组患者的Rhodes评分明显低于S组患者，差异显著（P<0.05），有统计学意义。在术后其余时间点，两组患者的Rhodes评分相比较，差异不显著（P>0.05），无统计学意义。结论：将异丙酚用于妇科腔镜手术的诱导麻醉及维持麻醉可有效预防患者在术后1 h发生PONV。%[ABSTRACT]Objective To investigate the effects of propofol and sevoflurane on post-operative nausea and vomiting in patients undergoing gynecologic laparoscopic surgeries. Methods Thirty-eight patients (ASAⅠ~Ⅱ) who underwent gynecologic laparoscopic surgery were enrolled in this study and were randomly divided into two groups (n=19): propofol group (P group) and sevoflurane group (S group). Patients in P group were anesthetized with propofol during the entire anesthetic period, while patients in S group received 2.0 mg/kg of propofol intravenously for anesthesia induction, followed by sevoflurane inhalation. We studied the patients who had PONV and RINVR scores 1, 6, and 24 hours post-operatively. P group has a statistically lower incidence of PONV and lower RINVR than S group (P<0.05). Conclusions Propofol at induction and during maintenance of anesthesia can be used to prevent PONV within 1 hour post-operatively in patients undergoing gynecologic laparoscopic surgeries.
展开▼
