3-（2-氯-4-三氟甲基苯氧基）苯甲酸合成工艺的改进

摘要

通过优化3-(2-氯-4-三氟甲基苯氧基)苯甲酸的生产工艺条件，显著降低了氟磺胺草醚缩合工序劳动强度、原料和能源消耗，减轻了环境污染，提高了中间体三氟羧草醚的含量和收率，进而大幅度降低了氟磺胺草醚原药的生产成本。%Through optimizing production process conditions of 3- (2-chloro-4- (trifluoromethyl) phenoxy) benzoic acid, labour intensity, raw materials and energy consumption during fomesafen condensation were significantly reduced as well as environmental pollution, the yield and content of intermediate acifluorfen were improved, which can greatly reduce the production cost of fomesafen drug.