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《海岸生命医学杂志(英文版)》
>Preliminary study on synergistic combinations of raw honey with gentamicin against Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa of veterinary origin
Preliminary study on synergistic combinations of raw honey with gentamicin against Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa of veterinary origin
Objective: To search for further synergistic combinations of gentamicin and raw honey that might have potential in treating wounds. Methods: The antibacterial activity and synergistic interaction of raw honey and gentamicin was assessed by using agar well diffusion method. Two Gram-negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 2154) bacteria were selected for antibacterial activity assay. The cultures of bacteria were maintained in their appropriate agar slants at 4 °C throughout the study and used as stock cultures. Results: Raw honey and gentamicin interacted synergistically to inhibit Escherichia coli and Pseudomonas aeruginosa. Conclusions: These results suggest that combinations of raw honey and gentamicin have therapeutic benefits in prophylaxis of infections caused by multidrug-resistant Gram-negative bacilli.
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