Evaluation of gamma interferon assay for detection of bovine tuberculosis in inactive foot and mouth disease vaccine administered cattle

摘要

Objective:To investigate the relationship between inactive foot and mouth disease virus (FMDV) vaccination and result of gamma interferon (IFN-γ) assay for tuberculosis in cattle negative for bovine tuberculosis. Methods:A total of 300 tuberculosis-negative cattles were subcutaneously vaccinated with inactive FMD vaccine. Nine hundred blood samples were collected from the same 300 cattles after 7, 15, and 30 days of vaccination. Then, all samples were tested with IFN-γ assay for tuberculosis. Results:A total of 900 blood samples were tested with IFN-γ assay for tuberculosis and all of the samples were found negative for bovine tuberculosis. Conclusions:Our results indicate that inactive FMD vaccination in cattle do not affect results of IFN-γ assay for tuberculosis.