乳腺可视化触诊成像系统在乳腺癌筛查中的应用

摘要

Objective To investigate the value of visualized palpation breast imaging system ( SureTouch) in breast cancer screening. Methods A total of 110 patients with breast masses were found in health examination in our hospital from December 2012 to December 2013, and all the patients were confirmed by SureTouch, B-ultrasound and X-ray mammography. The imaging data was retrospectively analyzed and the ROC curve was made to compare the diagnostic efficacy of the three methods. Results The results were confirmed by pathology. There were 63 cases of breast cancer and 47 cases of benign tumors. The areas under the ROC curve of SureTouch, B-ultrasound and X-ray mammography were 0. 887, 0. 863 and 0. 821, respectively. The sensitivity, specificity and accuracy of SureTouch examination were 0. 873, 0. 766, and 0. 827, respective-ly. The sensitivity of SureTouch was significantly higher than that of X-ray mammography (χ2 =2. 478, P=0. 008), but the difference was not significant when compared to B-ultrasound examination (χ2 =4. 721, P=0. 051);The specificity of Sure-Touch was lower than that of B-ultrasound examination (χ2 =3. 027, P=0. 046), but no statistical significance was found when compared to X-ray mammography (χ2 =4. 970, P=0. 056); The accuracy of SureTouch was significantly higher than that of X-ray mammography (χ2 =3. 487, P=0. 026), but no significant difference was found when compared to that of B-ul-trasound examination (χ2 =4. 986, P=0. 063). The sensitivity of SureTouch combined with B-ultrasound or X-ray mammog-raphy in diagnosis of breast cancer was significantly higher than that of any single test method. Conclusion SureTouch is ex-pected to become an important mean of auxiliary examination of breast diseases. Combined application of SureTouch, B-ultra-sound and X-ray mammography can further improve the sensitivity in the diagnosis of early breast cancer.%目的：探讨乳腺可视化触诊成像系统( SureTouch )在乳腺癌筛查中的价值。方法选取2012年12月-2013年12月我院健康体检发现的乳腺肿块患者110例,均经SureTouch、B超、钼靶X线检查。回顾分析其影像检查资料,绘制受试者工作特征( ROC)曲线,比较3种检查方法的诊断效能。结果经病理证实,110例中乳腺癌63例,良性肿块者47例。 ROC曲线下面积SureTouch为0.887, B超为0.863,钼靶X线为0.821。 SureTouch检查的灵敏度、特异度、准确度分别为0.873、0.766、0.827,检查灵敏度显著高于钼靶X线检查(χ2=2.478,P=0．008),与B超检查比较差异无统计学意义(χ2=4.721,P=0．051)；检查特异度低于B超检查(χ2=3.027,P=0．046),与钼靶X线检查比较差异无统计学意义(χ2=4.970,P=0．056)；检查准确度显著高于钼靶X线检查(χ2=3.487,P=0．026),与B超检查比较差异无统计学意义(χ2=4.986,P=0．063)。 SureTouch联合B超或钼靶X线检查诊断乳腺癌的灵敏度显著高于单一检查。结论 SureTouch有望成为乳腺疾病辅助检查的又一重要手段。 SureTouch联合应用B超或钼靶X线检查,可进一步提高早期乳腺癌的诊断灵敏度。