糖尿病并脑梗死的发病及预后影响因素分析

摘要

目的探讨糖尿病并脑梗死患者的血糖、血脂、血压与其梗死灶最大直径、神经功能损伤、临床疗效、并发症和病死率的关系。方法60例糖尿病并脑梗死与60例非糖尿病脑梗死患者进行比较；糖尿病并脑梗死60例中血脂、血压增高亚组分别与血脂、血压正常亚组进行比较。结果糖尿病并脑梗死时多为主干支大灶性梗死，且神经功能损伤重，临床疗效差，并发症和病死率高。另外并发症和病死率均与高血糖、高血脂、高血压等呈正相关。结论血糖水平升高、高血脂、高血压可加重脑梗死，适当使用胰岛素降低血糖并降血脂、降血压对脑梗死治疗及预后是有益的。%Objective To explore the relationship between the serum glucoselevel,blood lipid and blood pressure and the cerebral infarction size,neurological deficits,morbidity outcome,complication and mortality in patients with diabetes complicated with cerebral infarction.Methods Comparison was performed between 60 cases of diabetes complicated with cerebral infarction and another 60 normal counterparts. Those having hyperlipemia and hyperpiesia were compared with those with normal blood lipid and blood pressure.Results Major focal infarction occurred in the main branch to diabetics when complicated with cerebral infarction,who had larger infarct size,more neurological deficits,worse morbidity outcome,more complications and higher mortality.Occurrence of complications and mortality were positively related with hyperglycemia,hyperlipemia and hyperpiesia.Conclusion Hyperglycemia,hyperlipemia and hyperpiesia are factors enhancing cerebral infarction and brain damage. Proper insulin administration to control blood glucose level,hyperlipemia and blood pressure is benefitial to the treatment and prognosis of cerebral infarction.