功能性消化不良伴抑郁、焦虑状态患者脑功能检查的临床分析

摘要

目的 研究功能性消化不良(FD)与精神心理因素的关系,探讨脑功能检查诊断FD伴抑郁焦虑状态患者的临床意义.方法 选取诊断为FD的100例患者及30例健康志愿者,进行宗氏焦虑自评量表(SAS)、宗氏抑郁自评量表(SDS)心理评估.分别行脑电图及脑电超慢涨落技术(ET)检查,比较FD组与对照组脑电图异常率及脑神经递质的差异.结果 FD组焦虑发生率为30％,抑郁发生率为33％,焦虑合并抑郁发生率为11％,对照组焦虑发生率为6.7％,抑郁发生率为10％,FD组SDS评分、SAS评分明显高于对照组(P0.05).结论 FD患者抑郁焦虑状态发生率、脑电图异常率高于普通人群,可能与脑内神经递质变化,脑功能紊乱有关.%Objective To investigate the relationship between functional dyspepsia (FD ) and mental psychological factors and explore the clinical significance of brain function check diagnosis on FD patients associated with anxiety and depression state.Methods Psychological assessments,Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)were performed on 100 FD patients and 30 healthy volunteers.Electroencephalogram (EEG)and encephalofluctuo gram technology (ET)were also performed to compare the abnormal rates and the differences of neurotransmitter between FD and control group.Results Of 100 FD patients,the incidence rates of anxiety,depression and both anxiety and depression states were 30％,33％ and 11％,respectively.Of 30 healthy volunteers,the incidence rates of anxiety and depression were 6.7％ and 10％,respectively.The scores of SDS and SAS in FD group were obviously higher than those of control group(P 0.05).Conclusion The incidence rate of anxiety and depression state and the abnormity of EEG in FD patients are much higher than common people,the reason is due to the inordinate changes of neurotransmitter in the brain.