老年高血压患者动态血压与认知功能的关系

摘要

目的 探讨动态血压参数与老年高血压患者认知功能的关系.方法 收集老年高血压患者60例进行24 h动态血压监测及简易智能状态检查表(MMSE)行认知功能测定,根据MMSE得分分为对照组(n=35)和减退组(n=25),比较两组患者动态血压参数有无差异.结果 对照组与减退组患者中24 h平均收缩压[(127.38±19.14)mm Hg vs (132.00 ±15.09)mm Hg]、白昼平均收缩压[(131.64±17.55)mm Hg vs (137.09 ±13.77)mm Hg]、夜间平均收缩压[(118.78±18.75)mm Hg vs (126.00 ±11.37 mm Hg)]、昼夜节律比[(15.89±7.45)% vs (10.74±4.89)%]比较,差异有统计学意义(P<0.05);24 h平均舒张压、白昼及夜间平均舒张压比较,差异无统计学意义(P>0.05).结论 收缩压、血压节律异常与老年高血压患者认知功能损害有关.%Objective To evaluate the relationship between ambulatory blood pressure and cognition function in the elderly hy pertension patient. Methods 60 patients with essential hypertension underwent 24 h ambulatory blood pressure monitoring and MMSE determination of cognitive function,then were divided into two groups according to MMSE,control group(n = 35) and cog nitive dysfunction group(n = 25). To compared between the two groups difference in ambulatory blood pressure parameters. Results The two groups:SBP[(127. 38 + 19. 14) mm Hg vs (132. 00 +15. 09)mm Hg] , DSBP[(131. 64+17. 55) mm Hg vs (137.09 +13.77)mm Hg] ,NSBP[(118. 78 + 18. 75)mm Hg vs (126. 00 +11.37 mm Hg)] ,Rate[(15. 89+7. 45)% vs (10. 74 + 4. 89) %]showed significant difference(P<0. 05) ,but the result of DBP,DDBP,NDBP was not significantly different in two groups (P>0.05). Conclusion SBP and circadian rhythm have direct connection with cognition function in the elderly hypertension pa tient.