22例口服抗血栓药相关脑出血患者的临床分析

摘要

目的 探讨口服抗血栓药相关脑出血(OAT-ICH)患者的临床特点.方法 回顾性分析该院2009年6月至2011年6月收治的22例OAT-ICH患者的临床资料.结果 患者预后和死亡率与发病年龄、格拉斯哥昏迷(GCS)评分、出血量、国际标准化比值(INR)、血肿是否扩大关系密切.结论 OAT-ICH具有出血量大,血肿扩大的持续时间长、发生率高、预后更差,凝血功能异常,GCS评分低等特点;防止血肿进一步扩大对改善预后、降低死亡率非常重要;手术治疗是口服OAT-ICH最主要方式,但手术风险大,围术期管理特别关键.%Objective To explore the clinical characteristics of oral antithrombotic therapy related intracerebral hemorrhage (OAT-ICH). Methods The clinic data of 22 cases of OAT-ICH was retrospectively reviewed. Results The prognosis and mortality is related to the age,Glasgow Coma Scale(GCS)score,volume of the hematoma,International Normalized Ratio(INR) and hema-toma expansion. Conclusion OAT-ICH has clinical characteristics of large hemotoma volume,common and long time frame for he-matoma expansion,worse prognosis if hematoma expansion happens,coagulation defects,low GCS score and so on;To improve the prognosis and lower the mortality, we should focus on preventing the hematoma expansion. Surgical therapy is the main treatment to OAT-ICH even if it has a high risk,more attention should be paid to the perioperative management.