首页> 中文期刊>重庆医学 >超声造影评价聚焦超声在治疗子宫肌瘤及腺肌病补充治疗中的应用

超声造影评价聚焦超声在治疗子宫肌瘤及腺肌病补充治疗中的应用

     

摘要

Objective To investigate the application of ultrasound visualization in instantly evaluation and supplement therapeu-tics in the treatment of uterine fibroids and adenomyosis with high intensity focused ultrasound (HIFU ) .Methods 57 patients with 67 uterine fibroids and 31 patients with 41 adenomyosis were treated with JC-200 HIFU treatment system and monitored the blood flow change in the lesion with B-ultrasound .Evaluated the curative effect with ablation ratio and ablation ratio after supplement therapeutics .Results The average ablation ratio of 57 uterine fibroids was(84 .6 ± 16 .1)% and the increased to(87 .0 ± 10 .7)% af-ter supplement therapeutics to 9 lesions with blood flow in the border of all .The changes were no significance(P>0 .05) .The aver-age ablation ratio of 31 adenomyosis was(62 ± 22 .7)% and increased to(74 ± 14 .7)% after supplement therapeutics to 11 lesions with blood flow in the border of all .The changes were statically significance(P<0 .05) .Conclusion Ultrasound visualization could be used to evaluate the area and extent of ablation with HIFU therapy ,it can clear lesions remaining parts and guiding the supple-ment therapeutics to improve the ablation ratio .Ultrasound visualization provided an evidence of therapeutics in the early period .%目的:探讨超声造影对高强度聚焦超声(HIFU )治疗子宫肌瘤及腺肌病即刻评价及补充治疗的应用价值。方法57例子宫肌瘤患者(67个病灶),31例子宫腺肌病患者(41个病灶),采用JC-200型 HIFU 治疗系统,在B超监控下对病灶进行HIFU治疗,治疗前、后即刻应用机载超声造影观察病灶血流灌注变化并及时引导补充治疗,计算消融率及补充治疗后消融率,对早期疗效作出判断。结果 HIFU治疗后超声造影显示57例子宫肌瘤患者平均消融率为(84.6±16.1)%,其中9例治疗后超声造影检查提示病灶边缘局部仍有灌注,及时补充治疗后57例患者平均消融率提高为(87.0±10.7)%,前后平均消融率比较差异无统计学意义( P>0.05)。31例子宫腺肌病患者平均消融率为(62.0±22.7)%,其中11例经补充治疗后31例最终平均消融率为(74.0±14.7)%,前后平均消融率比较差异有统计学意义(P<0.05)。结论超声造影可用于评价 HIFU治疗子宫肌瘤及腺肌病的消融范围及程度,明确病灶残存部位及时引导补充治疗,提高消融率,为早期疗效判断提供依据。

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